Research Associate, Disease Biology, In Vivo Pharmacology – South San Francisco

About Frontier Medicines

Frontier Medicines, located in South San Francisco, CA and Boston, MA, is a precision medicine company that has pioneered a powerful discovery and development platform designed to generate medicines against disease-causing proteins previously considered undruggable. We are deploying our technologies in chemoproteomics, covalent drug discovery, and machine learning to develop a pipeline of groundbreaking medicines against the most important drivers of disease. Frontier has been recognized as a Fierce 15 company and a C&EN Start-Up to Watch. Our lead program targets both the active and inactive forms of KRASG12C, a validated driver in a number of cancers that until recently has been undruggable. Our pipeline embodies our vision of boldly advancing science to defeat disease, starting with cancer.

About the Role

Frontier medicines is seeking a highly motivated individual to fill the position of Research Associate in the Disease Biology team’s In Vivo group. The successful candidate is expected to have a working knowledge of in vivo research and mouse models of oncology. This position requires working as part of a multidisciplinary team in a fast-paced drug-hunting environment. This position is located in South San Francisco.

Key Responsibilities
  • Actively participate in animal observations and care, cell culture and mouse model development. 
  • Execute key in vivo experiments to demonstrate efficacy of novel compounds.
  • Contribute to project teams and the preclinical development of lead assets to achieve project deliverables.
  • Effectively communicate with colleagues and stakeholders; engage in the science beyond the experimental objective.
  • Maintain a clear, detailed electronic laboratory notebook to document all experiments and findings.
  • Comply with best laboratory safety practices.
  • BS in a biological science (animal science, pharmacology, cellular biology or related discipline), with at least 2-4 years of relevant pharma/biotech experience.
  • Experience in cancer biology, working in oncology drug discovery project teams, rodent cancer model development and drug testing.
  • Experience with cell culture.
  • Experience with in vivo techniques, including dosing, blood collection, and model development.
  • Excellent communication, organization, and technical writing skills.
  • Willingness to learn and adapt quickly, take initiative when warranted, and thrive in a dynamic start-up environment.
  • A commitment to excellence, focus on high quality science and a professional working environment.
  • Legally authorized to work in the US.

To apply, please send your resume to